Animal models have been used as replacement of human physiology and anatomy from ancient times. The purpose of its use is to gain a better understanding of human ontogeny and physiology. Over the past decades, use of animal models have increased drastically which makes many thinkers to question the practice of using animals as models for experimentation. Overtime, genetically inbreed species have been used as animal models, providing a steady source of research subjects. Animal models are used to answer a variety of scientific queries like development of vaccines and assessment of medical therapies. Observation and testing on animal models have resulted in breakthrough in basic science and scientific researches. Animal modelling industry is moving towards models that appropriately mimic human conditions.
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Development of novel therapies fuel industry growth
The global animal model industry has witnessed increase in its demand owing to the surge in development of novel therapies. The number of diseases and genetic disorders have increased in modern era, demanding more novel drugs to cure them. Escalating need of novel drugs to suffice the growing demand and increment in R&D activities are other reasons that fuel the global animal model industry growth. Though the growth is rapid, there are certain factors that inhibit growth like high cost to study using the model and restricting regulatory framework.
Human vaccines are bound to be tested before approval. Animal models are largely used not only to create but also upgrade human vaccines. In fact, several regulatory authorities make it mandatory for the novel vaccines to go through trials on animal models before subjecting them to human beings. However, use of actual animals is now being replaced with the help of computational biology and bioinformatics methodologies. But such methodologies cannot be considered practically successful as they fail to identify pathogens and the subsequent reactions after vaccine intake. Animal models are used with the objective to enhance the understanding of drug efficacy.
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Transgenic animals are gaining momentum
Use of animal models is highly prevalent in Asian region and it can be counted as the next major destinations of animal models. Several factors are responsible for this growth such as diversifying research activities in European and American Pharmaceutical companies. Amongst the Asian countries, China, Malaysia, Singapore and India are anticipated to lead the animal model industry growth in coming years where China will acquire the larger share. Transgenic animals have gained momentum due to increase in preference for humanized and super-immunodeficit animal models. Government in China have been encouraging medical researches which accounts for its leading position in animal models industry.
North America is the region that is attracting major investments in animal model industry. Policy reforms in favor of animal model researches are being formed to stimulate funding schemes and investments. North America also leads animal model market in terms of academic & research institutes and revenue. Other regions like Korea, Europe and MEA are also riding high in the industry positioning. Growth in the industry in these regions is based on different factors like pharmaceutical companies, contract research organizations and biotechnology companies.
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